articleProceedings of the National Academy of SciencesJan 3, 2008GREEN OA

Slow-wave sleep and the risk of type 2 diabetes in humans

ETEsra TasaliRLRachel LeproultDADavid A. EhrmannEVEve Van Cauter

University of Chicago

PubMed
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Abstract

There is convincing evidence that, in humans, discrete sleep stages are important for daytime brain function, but whether any particular sleep stage has functional significance for the rest of the body is not known. Deep non-rapid eye movement (NREM) sleep, also known as slow-wave sleep (SWS), is thought to be the most "restorative" sleep stage, but beneficial effects of SWS for physical well being have not been demonstrated. The initiation of SWS coincides with hormonal changes that affect glucose regulation, suggesting that SWS may be important for normal glucose tolerance. If this were so, selective suppression of SWS should adversely affect glucose homeostasis and increase the risk of type 2 diabetes. Here…

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908
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Authors

4

Topics & keywords

Topics
Keywords
  • Endocrinology
  • Internal medicine
  • Non-rapid eye movement sleep
  • Slow-wave sleep
  • Type 2 diabetes
  • Sleep (system call)
  • Diabetes mellitus
  • Sleep Stages
UN Sustainable Development Goals
  • Good health and well-being
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