articlePLoS ONEJul 18, 2011GOLD OA

Long-Term Persistance of the Pathophysiologic Response to Severe Burn Injury

Sunnybrook Health Science Centre · Shriners Hospitals for Children - Galveston · +4 more institutions

PubMed
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Abstract

BACKGROUND: Main contributors to adverse outcomes in severely burned pediatric patients are profound and complex metabolic changes in response to the initial injury. It is currently unknown how long these conditions persist beyond the acute phase post-injury. The aim of the present study was to examine the persistence of abnormalities of various clinical parameters commonly utilized to assess the degree hypermetabolic and inflammatory alterations in severely burned children for up to three years post-burn to identify patient specific therapeutic needs and interventions. PATIENTS: Nine-hundred seventy-seven severely burned pediatric patients with burns over 30% of the total body surface admitted to our…

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