Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): Somatosensory abnormalities in 1236 patients with different neuropathic pain syndromes
Heidelberg University · University Hospital Schleswig-Holstein · +14 more institutions
Abstract
Neuropathic pain is accompanied by both positive and negative sensory signs. To explore the spectrum of sensory abnormalities, 1236 patients with a clinical diagnosis of neuropathic pain were assessed by quantitative sensory testing (QST) following the protocol of DFNS (German Research Network on Neuropathic Pain), using both thermal and mechanical nociceptive as well as non-nociceptive stimuli. Data distributions showed a systematic shift to hyperalgesia for nociceptive, and to hypoesthesia for non-nociceptive parameters. Across all parameters, 92% of the patients presented at least one abnormality. Thermosensory or mechanical hypoesthesia (up to 41%) was more frequent than hypoalgesia (up to 18% for…
Citation impact
- FWCI
- 34.48
- Percentile
- 100%
- References
- 65
Authors
24- CSClaudia S. MaierCorresponding
Heidelberg University, University Hospital Schleswig-Holstein, Ruhr University Bochum, BG University Hospital Bergmannsheil Bochum, Johannes Gutenberg University Mainz, University of Lübeck, Zero to Three, Ludwig-Maximilians-Universität München, University Hospital Heidelberg
- RBRalf Baron
University of Lübeck, Zero to Three, University Hospital Schleswig-Holstein
- TRThomas R. Tölle
Technical University of Munich
- ABAndreas Binder
University of Lübeck, University Hospital Schleswig-Holstein
- NBNiels Birbaumer
University of Tübingen
Topics & keywords
- Hypoesthesia
- Neuropathic pain
- Hypoalgesia
- Allodynia
- Medicine
- Hyperalgesia
- Nociception
- Anesthesia
- Good health and well-being