The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort

Cognitive abnormalities are common in Parkinson's disease, with important social and economic implications. Factors influencing their evolution remain unclear but are crucial to the development of targeted therapeutic strategies. We have investigated the development of cognitive impairment and dementia in Parkinson's disease using a longitudinal approach in a population-representative incident cohort (CamPaIGN study, n = 126) and here present the 5-year follow-up data from this study. Our previous work has implicated two genetic factors in the development of cognitive dysfunction in Parkinson's disease, namely the genes for catechol-O-methyltransferase (COMT Val(158)Met) and microtubule-associated protein tau…

• PU
  Parkinson's UK
• UO
  University of Cambridge
• FW
  Fonds Wetenschappelijk Onderzoek
• VR
  Vlaamse regering
• NI
  National Institutes of Health
• MR
  Medical Research Council

  Award: RG38582