articleHepatologyNov 23, 2012BRONZE OA

Association between noninvasive fibrosis markers and mortality among adults with nonalcoholic fatty liver disease in the United States

DKDonghee KimRWRay W. KimHJHwa Jung KimTMTerry M. Therneau

Seoul National University Hospital · Mayo Clinic in Arizona · +4 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

UNLABELLED: The clinical and public health significance of nonalcoholic fatty liver disease (NAFLD) is not well established. We investigated the long-term effect of NAFLD on mortality. This analysis utilized the National Health and Nutrition Examination Survey conducted in 1988-1994 and subsequent follow-up data for mortality through December 31, 2006. NAFLD was defined by ultrasonographic detection of hepatic steatosis in the absence of other known liver diseases. The presence and severity of hepatic fibrosis in subjects with NAFLD was determined by the NAFLD fibrosis score (NFS), the aspartate aminotransferase to platelet ratio index (APRI), and FIB-4 score. Of 11,154 participants, 34.0% had NAFLD--the…

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Authors

4

Topics & keywords

Keywords
  • Nonalcoholic fatty liver disease
  • Medicine
  • Internal medicine
  • Fibrosis
  • Liver fibrosis
  • Nonalcoholic steatohepatitis
  • Disease
  • Gastroenterology
UN Sustainable Development Goals
  • Good health and well-being
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