Aspirin “resistance” and risk of cardiovascular morbidity: systematic review and meta-analysis

To determine if there is a relation between aspirin "resistance" and clinical outcomes in patients with cardiovascular disease.

Systematic review and meta-analysis. DATA SOURCE: Electronic literature search without language restrictions of four databases and hand search of bibliographies for other relevant articles. REVIEW METHODS: Inclusion criteria included a test for platelet responsiveness and clinical outcomes. Aspirin resistance was assessed, using a variety of platelet function assays.