Transcatheter Aortic-Valve Replacement for Inoperable Severe Aortic Stenosis
Vascular Institute of New York · Cleveland Clinic · +13 more institutions
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Abstract
Background
Transcatheter aortic-valve replacement (TAVR) is the recommended therapy for patients with severe aortic stenosis who are not suitable candidates for surgery. The outcomes beyond 1 year in such patients are not known.
Methods
We randomly assigned patients to transfemoral TAVR or to standard therapy (which often included balloon aortic valvuloplasty). Data on 2-year outcomes were analyzed.
Results
A total of 358 patients underwent randomization at 21 centers. The rates of death at 2 years were 43.3% in the TAVR group and 68.0% in the standard-therapy group (P
Citation impact
1,339
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- FWCI
- 100.97
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- 100%
- References
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Authors
25Topics & keywords
Topics
Keywords
- Medicine
- Stenosis
- Valve replacement
- Aortic valve stenosis
- Cardiology
- Aortic valve replacement
- Internal medicine
- Aortic valve
UN Sustainable Development Goals
- Good health and well-being
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