articleJournal of Magnetic Resonance ImagingJul 23, 2002Closed access

Differentiation of clinically benign and malignant breast lesions using diffusion‐weighted imaging

YGYong GuoYCYou‐Quan CaiCZCai Zu-longYGYuangui GaoNANingyu An

PLA Navy General Hospital · The University of Texas MD Anderson Cancer Center · +2 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Materials And Methods

Fifty-two female subjects (mean age = 58 years, age range = 25-75 years) with histopathologically proven breast lesions underwent DWI of the breasts with a single-shot echo-planar imaging (EPI) sequence using large b values. The computed mean apparent diffusion coefficients (ADCs) of the breast lesions and cell density were then correlated.

Results

The ADCs varied substantially between benign breast lesions ((1.57 +/- 0.23) x 10(-3) mm(2)/second) and malignant breast lesions ((0.97 +/- 0.20) x 10(-3) mm(2)/second). In addition, the mean ADCs of the breast lesions correlated well with tumor cellularity (P

Citation impact

716
total citations
FWCI
4.22
Percentile
100%
References
28
Citations per year

Authors

8

Topics & keywords

Topics
Keywords
  • Medicine
  • Radiology
  • Diffusion MRI
  • Breast imaging
  • Effective diffusion coefficient
  • Breast tumor
  • Echo-planar imaging
  • Breast cancer
UN Sustainable Development Goals
  • Good health and well-being
No related works found for this paper.