reviewCurrent Opinion in OphthalmologyJul 11, 2006Closed access

Crosslinking treatment of progressive keratoconus: new hope

Klinik und Poliklinik für Psychotherapie und Psychosomatik

PubMed
Indexed incrossrefpubmed

Abstract

PURPOSE OF REVIEW: A new method has been introduced for the treatment of progressive keratoconus using collagen crosslinking by the photosensitzer riboflavin and ultraviolet A-light. Biomechanical measurements have shown an impressive increase in corneal rigidity of 328.9% in human corneas after crosslinking. RECENT FINDINGS: The 3 and 5-year results of the Dresden clinical study have shown that in all treated 60 eyes the progression of keratoconus was at least stopped ('freezing'). In 31 eyes there also was a slight reversal and flattening of the keratoconus by up to 2.87 diopters. Best corrected visual acuity improved slightly by 1.4 lines. So far, over 150 keratoconus patients have received crosslinking…

Citation impact

657
total citations
FWCI
18.60
Percentile
100%
References
29
Citations per year

Authors

1

Topics & keywords

Keywords
  • Keratoconus
  • Medicine
  • Ophthalmology
  • Cornea
  • Corneal collagen cross-linking
  • Dioptre
  • Ultraviolet light
  • Corneal transplantation
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