articleAmerican Journal of Physical AnthropologyJan 19, 2006Closed access

Who's afraid of the big bad Wolff?: “Wolff's law” and bone functional adaptation

Johns Hopkins University · Johns Hopkins Medicine · +2 more institutions

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Abstract

"Wolff's law" is a concept that has sometimes been misrepresented, and frequently misunderstood, in the anthropological literature. Although it was originally formulated in a strict mathematical sense that has since been discredited, the more general concept of "bone functional adaptation" to mechanical loading (a designation that should probably replace "Wolff's law") is supported by much experimental and observational data. Objections raised to earlier studies of bone functional adaptation have largely been addressed by more recent and better-controlled studies. While the bone morphological response to mechanical strains is reduced in adults relative to juveniles, claims that adult morphology reflects only…

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