Molecular Diagnosis of Burkitt's Lymphoma
National Institutes of Health · National Cancer Institute · +14 more institutions
Indexed incrossrefpubmed
Abstract
Background
The distinction between Burkitt's lymphoma and diffuse large-B-cell lymphoma is crucial because these two types of lymphoma require different treatments. We examined whether gene-expression profiling could reliably distinguish Burkitt's lymphoma from diffuse large-B-cell lymphoma.
Methods
Tumor-biopsy specimens from 303 patients with aggressive lymphomas were profiled for gene expression and were also classified according to morphology, immunohistochemistry, and detection of the t(8;14) c-myc translocation.
Citation impact
903
total citations
- FWCI
- 41.37
- Percentile
- 100%
- References
- 33
Citations per year
Authors
38Topics & keywords
Topics
Keywords
- Lymphoma
- Burkitt's lymphoma
- Medicine
- Gene expression profiling
- Diffuse large B-cell lymphoma
- Pathology
- BCL10
- Cancer research
No related works found for this paper.