The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
University of Pennsylvania · Memorial Sloan Kettering Cancer Center · +2 more institutions
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Abstract
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1,981
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16Topics & keywords
Topics
Keywords
- IDH1
- IDH2
- Enzyme
- Biology
- Isocitrate dehydrogenase
- Biochemistry
- Feature (linguistics)
- Leukemia
UN Sustainable Development Goals
- Good health and well-being
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