Colloidal nanoparticles as advanced biological sensors
NIHR Imperial Biomedical Research Centre · Imperial College London
Abstract
Colloidal nanoparticle biosensors have received intense scientific attention and offer promising applications in both research and medicine. We review the state of the art in nanoparticle development, surface chemistry, and biosensing mechanisms, discussing how a range of technologies are contributing toward commercial and clinical translation. Recent examples of success include the ultrasensitive detection of cancer biomarkers in human serum and in vivo sensing of methyl mercury. We identify five key materials challenges, including the development of robust mass-scale nanoparticle synthesis methods, and five broader challenges, including the use of simulations and bioinformatics-driven experimental approaches…
Citation impact
- FWCI
- 48.65
- Percentile
- 100%
- References
- 105
Authors
3Topics & keywords
- Biosensor
- Nanotechnology
- Nanoparticle
- Computer science
- Biochemical engineering
- Materials science
- Engineering