Genome sequence of the lignocellulose degrading fungus Phanerochaete chrysosporium strain RP78

White rot fungi efficiently degrade lignin, a complex aromatic polymer in wood that is among the most abundant natural materials on earth. These fungi use extracellular oxidative enzymes that are also able to transform related aromatic compounds found in explosive contaminants, pesticides and toxic waste. We have sequenced the 30-million base-pair genome of Phanerochaete chrysosporium strain RP78 using a whole genome shotgun approach. The P. chrysosporium genome reveals an impressive array of genes encoding secreted oxidases, peroxidases and hydrolytic enzymes that cooperate in wood decay. Analysis of the genome data will enhance our understanding of lignocellulose degradation, a pivotal process in the global…

• UD
  U.S. Department of Energy

  Awards: AC03-76SF00098, AC05-00OR22725, W-7405, 7405-Eng-48, FG02-87ER13712, DE-FG02-, W-7405-ENG-36, DE-AC05, DE-FG02, 00OR22725
• B
  Battelle

  Awards: DE-AC05, DE-AC05-00OR22725
• LL
  Lawrence Livermore National Laboratory

  Awards: -7405-Eng-48, DE-AC05-00OR22725, W-7405-ENG-36, W-7405-Eng-48
• OR
  Oak Ridge National Laboratory

  Award: AC05-00OR22725
• LA
  Los Alamos National Laboratory

  Awards: DE-AC05-00OR22725, W-7405-ENG-36