Brca1 breast tumors contain distinct CD44+/CD24- and CD133+cells with cancer stem cell characteristics
National Cancer Institute · Center for Cancer Research
Indexed incrossrefdoajpubmed
Abstract
Introduction
Whether cancer stem cells occur in BRCA1-associated breast cancer and contribute to therapeutic response is not known.
Methods
We generated and characterized 16 cell lines from five distinct Brca1deficient mouse mammary tumors with respect to their cancer stem cell characteristics.
Citation impact
660
total citations
- FWCI
- 29.09
- Percentile
- 100%
- References
- 46
Citations per year
Authors
6- MHMollie H. WrightCorresponding
National Cancer Institute, Center for Cancer Research
- AMAnna Maria Calcagno
National Cancer Institute, Center for Cancer Research
- CDCrystal D. Salcido
National Cancer Institute, Center for Cancer Research
- MDMarisa D Carlson
National Cancer Institute, Center for Cancer Research
- SVSuresh V. Ambudkar
National Cancer Institute, Center for Cancer Research
Topics & keywords
Topics
Keywords
- Surgical oncology
- CD24
- CD44
- Breast cancer
- Cancer stem cell
- Medicine
- Cancer research
- Stem cell
UN Sustainable Development Goals
- Good health and well-being
No related works found for this paper.