Intestinal microbiota in patients with nonalcoholic fatty liver disease
University Health Network · Hospital for Sick Children · +2 more institutions
Abstract
UNLABELLED: Despite evidence that the intestinal microbiota (IM) is involved in the pathogenesis of obesity, the IM composition of patients with nonalcoholic fatty liver disease (NAFLD) has not been well characterized. This prospective, cross-sectional study was aimed at identifying differences in IM between adults with biopsy-proven NAFLD (simple steatosis [SS] or nonalcoholic steatohepatitis [NASH]) and living liver donors as healthy controls (HC). Fifty subjects were included: 11 SS, 22 NASH, and 17 HC. One stool sample was collected from each participant. Quantitative real-time polymerase chain reaction was used to measure total bacterial counts, Bacteroides/Prevotella (herein referred to as…
Citation impact
- FWCI
- 23.33
- Percentile
- 100%
- References
- 53
Authors
8- MMMarialena Mouzaki
University Health Network, Hospital for Sick Children, Toronto General Hospital
- EMElena M. Comelli
University of Toronto
- BMBianca M. Arendt
University Health Network, Toronto General Hospital
- JBJulia Bonengel
University Health Network, Toronto General Hospital
- SFScott Fung
University Health Network, University of Toronto, Toronto General Hospital
Topics & keywords
- Bacteroidetes
- Nonalcoholic fatty liver disease
- Gastroenterology
- Internal medicine
- Bacteroides
- Body mass index
- Fatty liver
- Biology