reviewNew England Journal of MedicineMar 19, 2003Closed access

The Chromogranin–Secretogranin Family

LTLaurent TaupenotKLKimberly L. HarperDTDaniel T. O’Connor

University of California, San Diego · VA San Diego Healthcare System

PubMed
Indexed incrossrefpubmed

Abstract

The members of the chromogranin–secretogranin family of peptide hormones, biogenic amines, and neurotransmitters are enclosed within vesicles in the neuroendocrine system and a variety of neurons. These granins, the chief of which is chromogranin A, participate in sympathoadrenal activity and serve as markers of neuroendocrine tumors, especially pheochromocytoma.

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Authors

3

Topics & keywords

Topics
Keywords
  • Chromogranin A
  • Pheochromocytoma
  • Sympathoadrenal system
  • Vesicle
  • Medicine
  • Endocrinology
  • Internal medicine
  • Hormone
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