reviewJournal of Cerebral Blood Flow & MetabolismJun 27, 2012BRONZE OA

Inflammatory Cytokines in Experimental and Human Stroke

KLKate Lykke LambertsenKBKnut BiberBFBente Finsen

University of Southern Denmark · University of Freiburg

PubMed
Indexed incrossrefpubmed

Abstract

Inflammation is a hallmark of stroke pathology. The cytokines, tumor necrosis factor (TNF), interleukin (IL)-1, and IL-6, modulate tissue injury in experimental stroke and are therefore potential targets in future stroke therapy. The effect of these cytokines on infarct evolution depends on their availability in the ischemic penumbra in the early phase after stroke onset, corresponding to the therapeutic window (

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Authors

3

Topics & keywords

Topics
Keywords
  • Penumbra
  • Microglia
  • Tumor necrosis factor alpha
  • Stroke (engine)
  • Medicine
  • Proinflammatory cytokine
  • Inflammation
  • Context (archaeology)
UN Sustainable Development Goals
  • Good health and well-being
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