Improvement in Aqueous Solubility in Small Molecule Drug Discovery Programs by Disruption of Molecular Planarity and Symmetry

ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTImprovement in Aqueous Solubility in Small Molecule Drug Discovery Programs by Disruption of Molecular Planarity and SymmetryMinoru Ishikawa* and Yuichi HashimotoView Author Information Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan*Phone: +81.3.5841.7849. Fax: +81.3.5841.8495. E-mail: [email protected]Cite this: J. Med. Chem. 2011, 54, 6, 1539–1554Publication Date (Web):February 23, 2011Publication History Received19 October 2010Published online23 February 2011Published inissue 24 March 2011https://pubs.acs.org/doi/10.1021/jm101356phttps://doi.org/10.1021/jm101356preview-articleACS…

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  Japan Society for the Promotion of Science