reviewJournal of Cellular and Molecular MedicineOct 16, 2008BRONZE OA

miR‐21: a small multi‐faceted RNA

AMAnna M. KrichevskyGGGalina Gabriely

Brigham and Women's Hospital · Harvard University

PubMed
Indexed incrossrefdoajpubmed

Abstract

MiR‐21 expression in cancer and other diseases Mechanisms of miR‐21 elevation in cancer: multi‐level regulatory control Transcriptional control Post‐trancriptional regulation miR‐21 functions in cancer Identification of direct miR‐21 targets miR‐21 in gliomas: targeting cell cycle, apoptosis and invasion miR‐21 networking and feedback regulation miR‐21 as a diagnostic and prognostic marker Potential therapeutic target Acknowledgements Abstract More than 1000 microRNAs (miRNAs) are expressed in human cells, some tissue or cell type specific, others considered as house‐keeping molecules. Functions and direct mRNA targets for some miRNAs have been relatively well studied over the last years. Every miRNA…

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995
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21.28
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100%
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117
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Authors

2

Topics & keywords

Topics
Keywords
  • Oncomir
  • microRNA
  • Biology
  • Computational biology
  • Regulation of gene expression
  • Biomarker
  • Gene
  • Bioinformatics
UN Sustainable Development Goals
  • Good health and well-being
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