Deterministic Diffusion Fiber Tracking Improved by Quantitative Anisotropy

Diffusion MRI tractography has emerged as a useful and popular tool for mapping connections between brain regions. In this study, we examined the performance of quantitative anisotropy (QA) in facilitating deterministic fiber tracking. Two phantom studies were conducted. The first phantom study examined the susceptibility of fractional anisotropy (FA), generalized factional anisotropy (GFA), and QA to various partial volume effects. The second phantom study examined the spatial resolution of the FA-aided, GFA-aided, and QA-aided tractographies. An in vivo study was conducted to track the arcuate fasciculus, and two neurosurgeons blind to the acquisition and analysis settings were invited to identify false…

• NS
  National Science Council

  Awards: NSC100-2321-B-002-015, NSC100-3112-B-002-016, NSC100-
• NI
  National Institutes of Health

  Award: U01MH093765
• NI
  National Institute of Mental Health

  Award: U01MH093765