Reactome knowledgebase of human biological pathways and processes
Cold Spring Harbor Laboratory · European Bioinformatics Institute · +5 more institutions
Abstract
Reactome (http://www.reactome.org) is an expert-authored, peer-reviewed knowledgebase of human reactions and pathways that functions as a data mining resource and electronic textbook. Its current release includes 2975 human proteins, 2907 reactions and 4455 literature citations. A new entity-level pathway viewer and improved search and data mining tools facilitate searching and visualizing pathway data and the analysis of user-supplied high-throughput data sets. Reactome has increased its utility to the model organism communities with improved orthology prediction methods allowing pathway inference for 22 species and through collaborations to create manually curated Reactome pathway datasets for species…
Citation impact
- FWCI
- 39.72
- Percentile
- 100%
- References
- 17
Authors
20- LMLisa MatthewsCorresponding
Cold Spring Harbor Laboratory
- GGGopal Gopinath
European Bioinformatics Institute, St. John's University, Lawrence Berkeley National Laboratory, Cold Spring Harbor Laboratory
- MGMarc Gillespie
European Bioinformatics Institute, St. John's University, Lawrence Berkeley National Laboratory, Cold Spring Harbor Laboratory
- MCMichael Caudy
European Bioinformatics Institute, St. John's University, Lawrence Berkeley National Laboratory, Cold Spring Harbor Laboratory
- DCDavid Croft
European Bioinformatics Institute, St. John's University, Lawrence Berkeley National Laboratory, Cold Spring Harbor Laboratory
Topics & keywords
- Biology
- Computational biology
- Inference
- Software
- Computer science
- Model organism
- Data mining
- Gene