A Long-Term Study of Prognosis in Monoclonal Gammopathy of Undetermined Significance
Mayo Clinic in Arizona · Cancer Research And Biostatistics · +1 more institution
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Abstract
Background
A monoclonal gammopathy of undetermined significance (MGUS) occurs in up to 2 percent of persons 50 years of age or older. Reliable predictors of progression have not been identified, and information on prognosis is limited.
Methods
We identified 1384 patients residing in southeastern Minnesota in whom MGUS was diagnosed at the Mayo Clinic from 1960 through 1994. The primary end point was progression to multiple myeloma or another plasma-cell cancer.
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Authors
7- RARobert A. KyleCorresponding
Mayo Clinic in Arizona
- TMTerry M. Therneau
Cancer Research And Biostatistics
- SVS. Vincent Rajkumar
Palmetto Hematology Oncology
- JRJanice R. Offord
Cancer Research And Biostatistics, Mayo Clinic in Arizona
- DRDirk R. Larson
Cancer Research And Biostatistics, Mayo Clinic in Arizona
Topics & keywords
Topics
Keywords
- Medicine
- Monoclonal gammopathy of undetermined significance
- Multiple myeloma
- Internal medicine
- Macroglobulinemia
- Waldenstrom macroglobulinemia
- Amyloidosis
- Gastroenterology
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