Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1
Broad Institute · Whitehead Institute for Biomedical Research · +3 more institutions
Indexed incrossrefpubmed
Abstract
No abstract available for this paper.
Citation impact
1,402
total citations
- FWCI
- 24.67
- Percentile
- 100%
- References
- 45
Citations per year
Authors
9- DADavid A. GuertinCorresponding
Broad Institute, Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
- DMDeanna M. Stevens
Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
- CCCarson C. Thoreen
Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
- AAAurora A. Burds
Center for Cancer Research, Massachusetts Institute of Technology
- NYNada Y. Kalaany
Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
Topics & keywords
Keywords
- Biology
- mTORC2
- P70-S6 Kinase 1
- Protein kinase B
- PI3K/AKT/mTOR pathway
- Cell biology
- mTORC1
- Signal transduction
No related works found for this paper.