Specific interactions between silver(i) ions and cytosine–cytosine pairs in DNA duplexes
Kanagawa University · Tokyo Metropolitan University · +2 more institutions
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Abstract
Very specific binding of the Ag(i) ion unexpectedly stabilized DNA duplexes containing the naturally occurring cytosine-cytosine (C-C) mismatch-base pair; because the C-C pair selectively binds to the Ag(i) ion, we developed a DNA-based Ag(i) sensor that employed an oligodeoxyribonucleotide containing C-C pairs used for Ag(i) binding sites.
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Topics
Keywords
- Cytosine
- DNA
- Chemistry
- Ion
- Base pair
- Crystallography
- Stereochemistry
- Biochemistry
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