Broad domain generality in focal regions of frontal and parietal cortex
McGovern Institute for Brain Research · Institute of Cognitive and Brain Sciences · +4 more institutions
Abstract
Unlike brain regions that respond selectively to specific kinds of information content, a number of frontal and parietal regions are thought to be domain- and process-general: that is, active during a wide variety of demanding cognitive tasks. However, most previous evidence for this functional generality in humans comes from methods that overestimate activation overlap across tasks. Here we present functional MRI evidence from single-subject analyses for broad functional generality of a specific set of brain regions: the same sets of voxels are engaged across tasks ranging from arithmetic to storing information in working memory, to inhibiting irrelevant information. These regions have a specific topography,…
Citation impact
- FWCI
- 20.37
- Percentile
- 100%
- References
- 100
Authors
3- EFEvelina FedorenkoCorresponding
McGovern Institute for Brain Research, Institute of Cognitive and Brain Sciences, Massachusetts Institute of Technology
- JDJohn Duncan
MRC Cognition and Brain Sciences Unit, University of Oxford, Medical Research Council
- NKNancy Kanwisher
McGovern Institute for Brain Research, Massachusetts Institute of Technology
Topics & keywords
- Generality
- Cognition
- Posterior parietal cortex
- Cognitive psychology
- Neuroimaging
- Cognitive neuroscience
- Perception
- Psychology
- Quality Education
Funding
- NSNational Science FoundationAwards: 057522, 0904625
- EMEllison Medical Foundation
- MIMassachusetts Institute of Technology
- MIMcGovern Institute for Brain Research, Massachusetts Institute of Technology
- MRMedical Research Council
- NINational Institute of Child Health and Human Development
- EKEunice Kennedy Shriver National Institute of Child Health and Human Development