3D Bioprinting of Vascularized, Heterogeneous Cell‐Laden Tissue Constructs

A new bioprinting method is reported for fabricating 3D tissue constructs replete with vasculature, multiple types of cells, and extracellular matrix. These intricate, heterogeneous structures are created by precisely co-printing multiple materials, known as bioinks, in three dimensions. These 3D micro-engineered environments open new ­avenues for drug screening and fundamental studies of wound healing, angiogenesis, and stem-cell niches. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting…

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  Hansjörg Wyss Institute for Biologically Inspired Engineering, Harvard University