Recent Advances in Asymmetric Organocatalytic 1,4‐Conjugate Additions

Abstract Recent progress in the field of asymmetric organocatalytic 1,4‐conjugate addition reactions, regarded as belonging among the more synthetically important carbon–carbon bond‐forming reactions, is described. The focus is on some recent advances in the following selected reactions: additions of various nucleophiles to α,β‐unsaturated cyclic and acyclic enals, enones, vinyl sulfones and nitro olefins, addition of malonates and/or ketones to acyclic enones, or of aldehydes and ketones to vinyl ketones and nitro olefins, together with some multicomponent domino reactions. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)