Structural foundations of resting-state and task-based functional connectivity in the human brain
University of California, Santa Barbara · University of Pennsylvania · +5 more institutions
Abstract
Magnetic resonance imaging enables the noninvasive mapping of both anatomical white matter connectivity and dynamic patterns of neural activity in the human brain. We examine the relationship between the structural properties of white matter streamlines (structural connectivity) and the functional properties of correlations in neural activity (functional connectivity) within 84 healthy human subjects both at rest and during the performance of attention- and memory-demanding tasks. We show that structural properties, including the length, number, and spatial location of white matter streamlines, are indicative of and can be inferred from the strength of resting-state and task-based functional correlations…
Citation impact
- FWCI
- 23.50
- Percentile
- 100%
- References
- 55
Authors
12- AMAnn M. HermundstadCorresponding
University of California, Santa Barbara, University of Pennsylvania
- DSDanielle S. Bassett
University of California, Santa Barbara
- KBKevin Brown
University of Connecticut, University of California, Santa Barbara
- EAElissa Aminoff
Center for the Neural Basis of Cognition, Carnegie Mellon University
- DCDavid Clewett
University of Southern California
Topics & keywords
- Resting state fMRI
- Human brain
- White matter
- Functional connectivity
- Functional magnetic resonance imaging
- Neuroscience
- Brain mapping
- Task (project management)