Microdroplets in Microfluidics: An Evolving Platform for Discoveries in Chemistry and Biology
University of Cambridge · Radboud University Nijmegen
Abstract
Microdroplets in microfluidics offer a great number of opportunities in chemical and biological research. They provide a compartment in which species or reactions can be isolated, they are monodisperse and therefore suitable for quantitative studies, they offer the possibility to work with extremely small volumes, single cells, or single molecules, and are suitable for high-throughput experiments. The aim of this Review is to show the importance of these features in enabling new experiments in biology and chemistry. The recent advances in device fabrication are highlighted as are the remaining technological challenges. Examples are presented to show how compartmentalization, monodispersity, single-molecule…
Citation impact
- FWCI
- 58.04
- Percentile
- 100%
- References
- 245
Authors
7Topics & keywords
- Microfluidics
- Nanotechnology
- Compartmentalization (fire protection)
- Chemical biology
- Throughput
- Computer science
- Synthetic biology
- Biochemical engineering
- Life below water