reviewClinical Microbiology ReviewsJan 1, 2015BRONZE OA

Current and Past Strategies for Bacterial Culture in Clinical Microbiology

JLJean‐Christophe LagierSESophie EdouardIPIsabelle PagnierOMOleg MediannikovMDMichel Drancourt

Centre National de la Recherche Scientifique · Inserm · +3 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

A pure bacterial culture remains essential for the study of its virulence, its antibiotic susceptibility, and its genome sequence in order to facilitate the understanding and treatment of caused diseases. The first culture conditions empirically varied incubation time, nutrients, atmosphere, and temperature; culture was then gradually abandoned in favor of molecular methods. The rebirth of culture in clinical microbiology was prompted by microbiologists specializing in intracellular bacteria. The shell vial procedure allowed the culture of new species of Rickettsia. The design of axenic media for growing fastidious bacteria such as Tropheryma whipplei and Coxiella burnetii and the ability of amoebal coculture…

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598
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19.97
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100%
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414
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Authors

6

Topics & keywords

Topics
Keywords
  • Fastidious organism
  • Microbiology
  • Biology
  • Axenic
  • Microbiological culture
  • Bacteria
  • Genetics
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