CuBr-Catalyzed Efficient Alkynylation of sp 3 C−H Bonds Adjacent to a Nitrogen Atom
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Abstract
A simple and effective catalytic method to construct propargylamine was developed by using copper bromide and tert-BuOOH via a combination of sp3 C-H bond and sp C-H bond activations followed by C-C bond formation.
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2Topics & keywords
Topics
Keywords
- Chemistry
- Alkynylation
- Catalysis
- Nitrogen atom
- Bromide
- Copper
- Nitrogen
- Atom (system on chip)
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