articleEnvironment InternationalJul 25, 2013HYBRID OA

Accumulation of perfluoroalkyl substances in human tissues

Institute of Environmental Assessment and Water Research · Institut d'Investigació Sanitària Pere Virgili · +3 more institutions

PubMed
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Abstract

Perfluoroalkyl substances (PFASs) are environmental pollutants with an important bioaccumulation potential. However, their metabolism and distribution in humans are not well studied. In this study, the concentrations of 21 PFASs were analyzed in 99 samples of autopsy tissues (brain, liver, lung, bone, and kidney) from subjects who had been living in Tarragona (Catalonia, Spain). The samples were analyzed by solvent extraction and online purification by turbulent flow and liquid chromatography coupled to tandem mass spectrometry. The occurrence of PFASs was confirmed in all human tissues. Although PFASs accumulation followed particular trends depending on the specific tissue, some similarities were found. In…

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