Carbon Nanoparticle-based Fluorescent Bioimaging Probes

Fluorescent nanoparticle-based imaging probes have advanced current labelling technology and are expected to generate new medical diagnostic tools based on their superior brightness and photostability compared with conventional molecular probes. Although significant progress has been made in fluorescent semiconductor nanocrystal-based biological labelling and imaging, the presence of heavy metals and the toxicity issues associated with heavy metals have severely limited the application potential of these nanocrystals. Here, we report a fluorescent carbon nanoparticle-based, alternative, nontoxic imaging probe that is suitable for biological staining and diagnostics. We have developed a chemical method to…

• DO
  Department of Biotechnology, Ministry of Science and Technology, India
• DO
  Department of Science and Technology, Ministry of Science and Technology, India
• CO
  Council of Scientific and Industrial Research, India
• NB
  National Brain Research Centre