Outcomes in Patients With De Novo Left Main Disease Treated With Either Percutaneous Coronary Intervention Using Paclitaxel-Eluting Stents or Coronary Artery Bypass Graft Treatment in the Synergy Between Percutaneous Coronary Intervention With TAXUS and Cardiac Surgery (SYNTAX) Trial
Uppsala University Hospital · San Raffaele University of Rome · +7 more institutions
Abstract
Background— The prospective, multinational, randomized Synergy Between Percutaneous Coronary Intervention With TAXUS and Cardiac Surgery (SYNTAX) trial was designed to assess the optimal revascularization strategy between percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG), for patients with left main (LM) and/or 3-vessel coronary disease. Methods and Results— This observational hypothesis-generating analysis reports the results of a prespecified powered subgroup of 705 randomized patients who had LM disease among the 1800 patients with de novo 3-vessel disease and/or LM disease randomized to PCI with paclitaxel-eluting stents or CABG in the SYNTAX trial. Major adverse cardiac…
Citation impact
- FWCI
- 76.72
- Percentile
- 100%
- References
- 39
Authors
13- MMMarie-Claude MoriceCorresponding
Uppsala University Hospital, San Raffaele University of Rome, Boston Scientific (United States), Heart Hospital Baylor Plano, Leipzig Heart Institute, Evanston Hospital, Mayo Clinic in Arizona, Hôpital Privé Jacques Cartier, Cardialysis (Netherlands)
- PWPatrick W. Serruys
Uppsala University Hospital, San Raffaele University of Rome, Boston Scientific (United States), Heart Hospital Baylor Plano, Leipzig Heart Institute, Evanston Hospital, Mayo Clinic in Arizona, Hôpital Privé Jacques Cartier, Cardialysis (Netherlands)
- APA. Pieter Kappetein
Uppsala University Hospital, San Raffaele University of Rome, Boston Scientific (United States), Heart Hospital Baylor Plano, Leipzig Heart Institute, Evanston Hospital, Mayo Clinic in Arizona, Hôpital Privé Jacques Cartier, Cardialysis (Netherlands)
- TFTed Feldman
Uppsala University Hospital, San Raffaele University of Rome, Boston Scientific (United States), Heart Hospital Baylor Plano, Leipzig Heart Institute, Evanston Hospital, Mayo Clinic in Arizona, Hôpital Privé Jacques Cartier, Cardialysis (Netherlands)
- ESElisabeth Ståhle
Uppsala University Hospital, San Raffaele University of Rome, Boston Scientific (United States), Heart Hospital Baylor Plano, Leipzig Heart Institute, Evanston Hospital, Mayo Clinic in Arizona, Cardialysis (Netherlands)
Topics & keywords
- Medicine
- Conventional PCI
- Percutaneous coronary intervention
- Cardiology
- Internal medicine
- Coronary artery disease
- Randomized controlled trial
- Revascularization
- Good health and well-being