articleNucleic Acids ResearchNov 20, 2014GOLD OA

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations

University of Liverpool · Universidad Autónoma de Coahuila · +2 more institutions

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Abstract

It has been 12 years since the Allele Frequency Net Database (AFND; http://www.allelefrequencies.net) was first launched, providing the scientific community with an online repository for the storage of immune gene frequencies in different populations across the world. There have been a significant number of improvements from the first version, making AFND a primary resource for many clinical and scientific areas including histocompatibility, immunogenetics, pharmacogenetics and anthropology studies, among many others. The most widely used part of AFND stores population frequency data (alleles, genes or haplotypes) related to human leukocyte antigens (HLA), killer-cell immunoglobulin-like receptors (KIR), major…

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Authors

11

Topics & keywords

Keywords
  • Biology
  • Human leukocyte antigen
  • Major histocompatibility complex
  • Allele
  • Allele frequency
  • Haplotype
  • Population
  • Immunology
UN Sustainable Development Goals
  • Good health and well-being
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