Hierarchical Organization of Human Cortical Networks in Health and Schizophrenia

The complex organization of connectivity in the human brain is incompletely understood. Recently, topological measures based on graph theory have provided a new approach to quantify large-scale cortical networks. These methods have been applied to anatomical connectivity data on nonhuman species, and cortical networks have been shown to have small-world topology, associated with high local and global efficiency of information transfer. Anatomical networks derived from cortical thickness measurements have shown the same organizational properties of the healthy human brain, consistent with similar results reported in functional networks derived from resting state functional magnetic resonance imaging (MRI) and…

• NI
  National Institutes of Health
• NI
  National Institute of Mental Health
• NI
  National Institute of Biomedical Imaging and Bioengineering