Protection by BCG Vaccine Against Tuberculosis: A Systematic Review of Randomized Controlled Trials
London School of Hygiene & Tropical Medicine · University of London · +8 more institutions
Abstract
Randomized trials assessing BCG vaccine protection against tuberculosis have widely varying results, for reasons that are not well understood.
We examined associations of trial setting and design with BCG efficacy against pulmonary and miliary or meningeal tuberculosis by conducting a systematic review, meta-analyses, and meta-regression.
Citation impact
- FWCI
- 22.41
- Percentile
- 100%
- References
- 52
Authors
11- PMPunam MangtaniCorresponding
London School of Hygiene & Tropical Medicine, University of London
- IAIbrahim Abubakar
University College London, London Centre for Neglected Tropical Disease Research, Public Health England
- CACono Ariti
London School of Hygiene & Tropical Medicine, University of London
- RBRebecca Beynon
University of Bristol
- LPLaura Pimpin
Medical Research Council, Public Health England, MRC Human Nutrition Research
Topics & keywords
- Medicine
- Tuberculosis
- Relative risk
- Tuberculin
- Miliary tuberculosis
- Confidence interval
- BCG vaccine
- Mycobacterium tuberculosis
- Good health and well-being