Elevated Striatal Dopamine Function Linked to Prodromal Signs of Schizophrenia

Howes, Oliver; Montgomery, Andrew; Asselin, Marie‐Claude; Murray, Robin; Valli, Isabel; Tabraham, P.; Bramon, Elvira; Valmaggia, Lucia; Johns, Louise; Broome, Matthew R.; McGuire, Philip; Grasby, Paul M.

doi:10.1001/archgenpsychiatry.2008.514

articleArchives of General PsychiatryJan 1, 2009GREEN OA

Elevated Striatal Dopamine Function Linked to Prodromal Signs of Schizophrenia

OHOliver Howes AMAndrew Montgomery MAMarie‐Claude Asselin RMRobin Murray IVIsabel Valli

King's College London · Medical Research Council · +1 more institution

PubMed

Indexed incrossrefpubmed

Abstract

Objectives

To determine whether striatal dopamine function is elevated in individuals with prodromal symptoms of schizophrenia before the onset of psychosis and to assess how this relates to the symptoms and neurocognitive impairment.

Design

Case-control study of in vivo striatal dopaminergic function.

Citation impact

737

total citations

FWCI: 29.56
Percentile: 100%
References: 53

Citations per year

Authors

12

Topics & keywords

Topics

Keywords

Schizophrenia (object-oriented programming)
Neurocognitive
Dopamine
Psychology
Psychosis
Psychiatry
Dopaminergic
Internal medicine

UN Sustainable Development Goals

Good health and well-being

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