Hypermutation of HIV-1 DNA in the Absence of the Vif Protein
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Abstract
The Vif (viral infectivity factor) protein of human immunodeficiency virus–1 (HIV-1) is essential for the production of infectious virus by T lymphocytes and macrophages, the natural targets for HIV-1 infection. Vif is dispensable for HIV infection in certain transformed cell lines (“permissive
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4Topics & keywords
Topics
Keywords
- Somatic hypermutation
- Human immunodeficiency virus (HIV)
- DNA
- Virology
- Genetics
- Biology
- Antibody
UN Sustainable Development Goals
- Good health and well-being
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