Abstract
Polycystic kidney diseases are inherited renal disorders due mainly to mutations in genes that regulate the development and function of cells that line renal tubules. This review outlines the clinical importance of polycystic kidney diseases and discusses the cell biology and molecular mechanisms that cause the formation of hundreds of cystic lesions in the renal parenchyma.
Citation impact
922
total citations
- FWCI
- 36.09
- Percentile
- 100%
- References
- 92
Citations per year
Authors
1Topics & keywords
Topics
Keywords
- Polycystic kidney disease
- Medicine
- Kidney
- Polycystic kidney
- Renal parenchyma
- Cilium
- Cystic kidney disease
- Disease
UN Sustainable Development Goals
- Good health and well-being
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