Growing Together and Growing Apart: Regional and Sex Differences in the Lifespan Developmental Trajectories of Functional Homotopy
Beijing Normal University · NYU Langone Health · +6 more institutions
Abstract
Functional homotopy, the high degree of synchrony in spontaneous activity between geometrically corresponding interhemispheric (i.e., homotopic) regions, is a fundamental characteristic of the intrinsic functional architecture of the brain. However, despite its prominence, the lifespan development of the homotopic resting-state functional connectivity (RSFC) of the human brain is rarely directly examined in functional magnetic resonance imaging studies. Here, we systematically investigated age-related changes in homotopic RSFC in 214 healthy individuals ranging in age from 7 to 85 years. We observed marked age-related changes in homotopic RSFC with regionally specific developmental trajectories of varying…
Citation impact
- FWCI
- 10.15
- Percentile
- 100%
- References
- 94
Authors
11- XZXi‐Nian ZuoCorresponding
Beijing Normal University, NYU Langone Health, New York University
- CKClare Kelly
NYU Langone Health, New York University
- ADAdriana Di Martino
University of Cagliari, New York University
- MMMaarten Mennes
NYU Langone Health, New York University
- DSDaniel S. Margulies
Max Planck Society, Max Planck Institute for Human Cognitive and Brain Sciences
Topics & keywords
- Neuroscience
- Functional connectivity
- Functional magnetic resonance imaging
- Psychology
- Amygdala
- Insula
- Biology