Extensive sampling of basidiomycete genomes demonstrates inadequacy of the white-rot/brown-rot paradigm for wood decay fungi

Basidiomycota (basidiomycetes) make up 32% of the described fungi and include most wood-decaying species, as well as pathogens and mutualistic symbionts. Wood-decaying basidiomycetes have typically been classified as either white rot or brown rot, based on the ability (in white rot only) to degrade lignin along with cellulose and hemicellulose. Prior genomic comparisons suggested that the two decay modes can be distinguished based on the presence or absence of ligninolytic class II peroxidases (PODs), as well as the abundance of enzymes acting directly on crystalline cellulose (reduced in brown rot). To assess the generality of the white-rot/brown-rot classification paradigm, we compared the genomes of 33…

• UD
  U.S. Department of Energy

  Awards: FC02-07ER64494, -AC02-05CH11231, 07ER64494, DE-FC02-07ER64494, 05CH11231, Contract DE-AC02-05CH11231, AC02-05CH11231, DE-AC02, DE-AC02-05CH11231, DE-AC02-
• JG
  Joint Genome Institute

  Awards: DE-AC02-05CH11231, AC02-05CH11231
• AN
  Agence Nationale de la Recherche

  Awards: ANR-11-LABX-0002-01, DE-AC02-05CH11231, ANR-11-LABX-0002
• FO
  Faculty of Health and Medical Sciences, University of Western Australia
• NI
  National Institutes of Health

  Award: DE-AC02-05CH11231
• OO
  Office of Science

  Awards: Contract DE-AC02-05CH11231, DE-FC02-07ER64494, FC02-07ER64494, AC02-05CH11231, -AC02-05CH11231, DE-AC02
• GL
  Great Lakes Bioenergy Research Center

  Awards: DE-FC02-07ER64494, DE-AC02-05CH11231
• DS
  Det Sundhedsvidenskabelige Fakultet, Københavns Universitet
• BA
  Biological and Environmental Research

  Awards: 05CH11231, DE-FC02-07ER64494, DE-AC02-05CH11231, AC02-05CH11231