articlePLoS GeneticsMar 19, 2009GOLD OA

A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose

FTFumihiko TakeuchiRMRalph McGinnisSBStéphane BourgeoisCBC. BarnesNENiclas Eriksson

Wellcome Sanger Institute · Karolinska University Hospital · +2 more institutions

PubMed
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Abstract

We report the first genome-wide association study (GWAS) whose sample size (1,053 Swedish subjects) is sufficiently powered to detect genome-wide significance (p

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Topics & keywords

Topics
Keywords
  • VKORC1
  • Warfarin
  • Genome-wide association study
  • CYP2C9
  • Single-nucleotide polymorphism
  • Biology
  • Internal medicine
  • Genetics
UN Sustainable Development Goals
  • Good health and well-being
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