What Is the Role for the Circumferential Margin in the Modern Treatment of Rectal Cancer?
University of Leeds · Radboud University Nijmegen · +1 more institution
Indexed incrossrefpubmed
Abstract
Methods
In the current review, the evidence for the importance of the CRM in more than 17,500 patients is reviewed, and the relevance of this assessment to modern treatment is assessed.
Results
We demonstrate that, after neoadjuvant therapy (both radiotherapy and radiochemotherapy), the predictive value of the CRM for local recurrence is significantly higher than when no preoperative therapy has been applied (hazard ratio [HR] = 6.3 v 2.0, respectively; P
Citation impact
1,008
total citations
- FWCI
- 22.27
- Percentile
- 100%
- References
- 71
Citations per year
Authors
2Topics & keywords
Topics
Keywords
- Medicine
- Colorectal cancer
- Total mesorectal excision
- Radiation therapy
- Margin (machine learning)
- Hazard ratio
- Resection margin
- Oncology
UN Sustainable Development Goals
- Good health and well-being
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