articleEnvironmental Science & TechnologyFeb 22, 2003Closed access

Strategic Survey of Therapeutic Drugs in the Rivers Po and Lambro in Northern Italy

Mario Negri Institute for Pharmacological Research · University of Insubria

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Abstract

A survey was done in the river Po (Italy) to check for therapeutic drugs in the environment. A number of pharmaceuticals were selected for analysis on the basis of high consumption and excretion as parent compound in humans. Eight sampling stations along the rivers Po and Lambro made it possible to plot the patterns of contamination in a highly populated region with a large number of animal farms. Atenolol, lincomycin, erythromycin, clarithromycin, bezafibrate, and furosemide were present at all the sampling sites, and other drugs were found only in some. Concentrations ranged from 0.1 to 250 ng/L, and several drugs exceeded the trigger value (10 ng/L) suggested by recent documents from the European Agency for…

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