A Structural MRI Study of Human Brain Development from Birth to 2 Years
University of North Carolina at Chapel Hill · University of Utah
Abstract
Brain development in the first 2 years after birth is extremely dynamic and likely plays an important role in neurodevelopmental disorders, including autism and schizophrenia. Knowledge regarding this period is currently quite limited. We studied structural brain development in healthy subjects from birth to 2. Ninety-eight children received structural MRI scans on a Siemens head-only 3T scanner with magnetization prepared rapid gradient echo T1-weighted, and turbo spin echo, dual-echo (proton density and T2 weighted) sequences: 84 children at 2-4 weeks, 35 at 1 year and 26 at 2 years of age. Tissue segmentation was accomplished using a novel automated approach. Lateral ventricle, caudate, and hippocampal…
Citation impact
- FWCI
- 40.74
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- 100%
- References
- 68
Authors
10Topics & keywords
- Brain size
- White matter
- Cerebellum
- Brain development
- Brain morphometry
- Neuroscience
- Psychology
- Human brain