articleReproductive Biology and EndocrinologyApr 25, 2015GOLD OA

A unique view on male infertility around the globe

Cleveland Clinic · Northeast Ohio Medical University · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

Background

Infertility affects an estimated 15% of couples globally, amounting to 48.5 million couples. Males are found to be solely responsible for 20-30% of infertility cases and contribute to 50% of cases overall. However, this number does not accurately represent all regions of the world. Indeed, on a global level, there is a lack of accurate statistics on rates of male infertility. Our report examines major regions of the world and reports rates of male infertility based on data on female infertility.

Methods

Our search consisted of systematic reviews, meta-analyses, and population-based studies by searching the terms "epidemiology, male infertility, and prevalence." We identified 16 articles for detailed study. We typically used the assumption that 50% of all cases of infertility are due to female factors alone, 20-30% are due to male factors alone, and the remaining 20-30% are due to a combination of male and female factors. Therefore, in regions of the world where male factor or rates of male infertility were not reported, we used this assumption to calculate general rates of male factor infertility.

Citation impact

2,378
total citations
FWCI
96.77
Percentile
100%
References
28
Citations per year

Authors

4

Topics & keywords

Keywords
  • Infertility
  • Male infertility
  • Demography
  • Epidemiology
  • Fertility
  • Medicine
  • Population
  • Female infertility
UN Sustainable Development Goals
  • Good health and well-being
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Funding