101 Labeled Brain Images and a Consistent Human Cortical Labeling Protocol

We introduce the Mindboggle-101 dataset, the largest and most complete set of free, publicly accessible, manually labeled human brain images. To manually label the macroscopic anatomy in magnetic resonance images of 101 healthy participants, we created a new cortical labeling protocol that relies on robust anatomical landmarks and minimal manual edits after initialization with automated labels. The "Desikan-Killiany-Tourville" (DKT) protocol is intended to improve the ease, consistency, and accuracy of labeling human cortical areas. Given how difficult it is to label brains, the Mindboggle-101 dataset is intended to serve as brain atlases for use in labeling other brains, as a normative dataset to establish…

• NI
  National Institutes of Health

  Awards: 1R03EB012461, P50 AG05681, R01 AG021910, MH071616, AG05681, U24 RR021382, P41RR015241, P01 AG03991, AG03991, R01 MH56584, P50 MH071616, 1R21NS064534
• NI
  National Institute of Mental Health

  Awards: R01 MH56584, P50 MH071616, MH071616
• NC
  National Center for Research Resources

  Award: U24 RR021382