MCScanX: a toolkit for detection and evolutionary analysis of gene synteny and collinearity
J. Craig Venter Institute · North China University of Science and Technology · +6 more institutions
Abstract
MCScan is an algorithm able to scan multiple genomes or subgenomes in order to identify putative homologous chromosomal regions, and align these regions using genes as anchors. The MCScanX toolkit implements an adjusted MCScan algorithm for detection of synteny and collinearity that extends the original software by incorporating 14 utility programs for visualization of results and additional downstream analyses. Applications of MCScanX to several sequenced plant genomes and gene families are shown as examples. MCScanX can be used to effectively analyze chromosome structural changes, and reveal the history of gene family expansions that might contribute to the adaptation of lineages and taxa. An integrated view…
Citation impact
- FWCI
- 14.78
- Percentile
- 100%
- References
- 76
Authors
12- YWYupeng Wang
J. Craig Venter Institute, North China University of Science and Technology, University of Georgia, Carnegie Department of Plant Biology
- HTHaibao Tang
J. Craig Venter Institute, North China University of Science and Technology, University of Georgia
- JDJeremy D. DeBarry
J. Craig Venter Institute, North China University of Science and Technology, University of Georgia
- XTXu Tan
J. Craig Venter Institute, North China University of Science and Technology, University of Georgia, Laboratoire Génome et Développement des Plantes, National Institute of Plant Genome Research
- JLJun Li
J. Craig Venter Institute, North China University of Science and Technology, University of Georgia, Laboratoire Génome et Développement des Plantes, Institute of Bioinformatics, National Institute of Plant Genome Research
Topics & keywords
- Synteny
- Biology
- Genome
- Collinearity
- Gene duplication
- Gene
- Genetics
- Computational biology